June 20, 2019 Peter Hoang Chief Executive Officer Marker Therapeutics, Inc. 3200 Southwest Freeway, Suite 2240 Houston, TX 77027 Re: Marker Therapeutics, Inc. Registration Statement on Form S-3 Filed June 14, 2019 File No. 333-232122 Dear Mr. Hoang: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tonya K. Aldave at (202) 551-3601 with any questions. Sincerely, Division of Corporation Finance Office of Healthcare & Insurance cc: Divakar Gupta, Esq.