101 - Document - Document and Entity Information link:calculationLink link:presentationLink link:definitionLink 103 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS link:calculationLink link:presentationLink link:definitionLink 104 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 105 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:calculationLink link:presentationLink link:definitionLink 106 - Statement - CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY (DEFICIT) AS RESTATED link:calculationLink link:presentationLink link:definitionLink 107 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS link:calculationLink link:presentationLink link:definitionLink 108 - Disclosure - Nature of Operations link:calculationLink link:presentationLink link:definitionLink 109 - Disclosure - Summary of Significant Accounting Policies link:calculationLink link:presentationLink link:definitionLink 110 - Disclosure - Net Loss Per Share Applicable to Common Shareholder link:calculationLink link:presentationLink link:definitionLink 111 - Disclosure - Research Agreements link:calculationLink link:presentationLink link:definitionLink 112 - Disclosure - Derivative Liability link:calculationLink link:presentationLink link:definitionLink 113 - Disclosure - Promissory Notes link:calculationLink link:presentationLink link:definitionLink 114 - Disclosure - Promissory Note, Related Party link:calculationLink link:presentationLink link:definitionLink 115 - Disclosure - Capital Stock link:calculationLink link:presentationLink link:definitionLink 116 - Disclosure - Income Taxes link:calculationLink link:presentationLink link:definitionLink 117 - Disclosure - Contingencies and Commitments link:calculationLink link:presentationLink link:definitionLink 118 - Disclosure - Summary of Significant Accounting Policies (Policies) link:calculationLink link:presentationLink link:definitionLink 119 - Disclosure - Net Loss Per Share Applicable to Common Shareholder (Tables) link:calculationLink link:presentationLink link:definitionLink 120 - Disclosure - Derivative Liability (Tables) link:calculationLink link:presentationLink link:definitionLink 121 - Disclosure - Capital Stock (Tables) link:calculationLink link:presentationLink link:definitionLink 122 - Disclosure - Income Taxes (Tables) link:calculationLink link:presentationLink link:definitionLink 123 - Disclosure - Nature of Operations - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 124 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 125 - Disclosure - Net Loss per Share Applicable to Common Shareholder - Net Loss per Share (Detail) link:calculationLink link:presentationLink link:definitionLink 126 - Disclosure - Research Agreements - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 127 - Disclosure - Derivative Liability - Valuation Methodology (Detail) link:calculationLink link:presentationLink link:definitionLink 128 - Disclosure - Derivative Liability - Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis (Detail) link:calculationLink link:presentationLink link:definitionLink 129 - Disclosure - Derivative Liability - Schedule of Changes in Level 3 Liabilities Measured at Fair Value (Detail) link:calculationLink link:presentationLink link:definitionLink 130 - Disclosure - Promissory Notes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 131 - Disclosure - Promissory Note, Related Party - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 132 - Disclosure - Capital Stock - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 133 - Disclosure - Capital Stock - Share Purchase Warrants (Detail) link:calculationLink link:presentationLink link:definitionLink 134 - Disclosure - Capital Stock - Share Purchase Options (Detail) link:calculationLink link:presentationLink link:definitionLink 135 - Disclosure - Capital Stock - Weighted Average Assumptions (Detail) link:calculationLink link:presentationLink link:definitionLink 136 - Disclosure - Income Taxes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 137 - Disclosure - Income Taxes - Summary of Effects of Temporary Differences that Give Rise to Significant Portions of the Deferred Tax Assets (Detail) link:calculationLink link:presentationLink link:definitionLink 138 - Disclosure - Income Taxes - Summary of Expected Tax Expense (Benefit) Based on the U.S. Federal Statutory Rate is Reconciled with the Actual Tax Provision (Benefit) (Detail) link:calculationLink link:presentationLink link:definitionLink 139 - Disclosure - Contingencies and Commitments - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink