Accounting Policies [Abstract] Accounting Policies [Abstract] Accounts Payable and Accrued Liabilities, Fair Value Disclosure Accounts payable and accrued liabilities Accounts Payable Settled In Amount Accounts Payable Settled In Amount Accounts payable settled in shares, Amount Accounts Payable Settled In Shares Accounts Payable Settled In Shares Accounts payable settled in shares, Share Accretion of interest on convertible debt. Accretion Of Interest On Convertible Debt Accretion of discount on convertible notes Accrued Liabilities Accrued liabilities AOCI Including Portion Attributable to Noncontrolling Interest, before Tax Accumulated other comprehensive loss AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Loss [Member] Additional Paid in Capital Additional paid-in capital Additional Paid-in Capital [Member] Additional Paid-In Capital Additions during year. Additions During Year Additions during the period Adjustments to additional paid in capital finders fee on warrants exercised. Adjustments To Additional Paid In Capital Finders Fee On Warrants Exercised Finders' fee on exercise of warrants Adjustments to Additional Paid in Capital, Warrant Issued Reclassification of Derivative Warrant Liabilities to Equity at exercise date Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash from operating activities: Aggregate purchase price of shares agreed to purchase under stock purchase agreement. Aggregate Purchase Price Of Shares Agreed To Purchase Under Stock Purchase Agreement Aggregate purchase price Amendment Flag Amendment Flag Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Excluded potentially dilutive securities Assets [Abstract] ASSETS Assets, Current Total Current Assets Assets, Current [Abstract] Current Assets Award Type [Axis] Award Type [Axis] Basis of Accounting, Policy [Policy Text Block] Basis of Presentation The entire disclosure for the capital stock. Capital Stock [Text Block] Capital Stock Cash CASH, END OF YEAR CASH, BEGINNING OF YEAR Cash Cash, Period Increase (Decrease) INCREASE IN CASH Class of Stock [Domain] Class of Stock [Domain] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Class of Warrant or Right, Exercise Price of Warrants or Rights Exercise price of warrants Class of warrant or right expiration period. Class Of Warrant Or Right Expiration Period Warrant expiration period Class of Warrant or Right, Number of Securities Called by Each Warrant or Right Number of securities callable by each warrant or right warrants Class of Warrant or Right, Number of Securities Called by Warrants or Rights Class of warrant or right, number of securities called by warrants or rights Class of Warrant or Right, Outstanding Number of Warrants, Ending balance Number of Warrants, Beginning balance Number of warrants issued Class of warrant or right outstanding exercised weighted average exercise price. Class Of Warrant Or Right Outstanding Exercised Weighted Average Exercise Price Weighted Average Exercise Price, Exercised Class of warrant or right outstanding extinguished or expired weighted average exercise price. Class Of Warrant Or Right Outstanding Extinguished Or Expired Weighted Average Exercise Price Weighted Average Exercise Price, Extinguished or expired Class of warrant or right outstanding issued weighted average exercise price. Class Of Warrant Or Right Outstanding Issued Weighted Average Exercise Price Weighted Average Exercise Price, Issued Class of warrant or right outstanding issued weighted average remaining life. Class Of Warrant Or Right Outstanding Issued Weighted Average Remaining Life Weighted Average Remaining Life, Warrants Issued Class Of Warrant Or Right Outstanding Weighted Average Exercise Price Class Of Warrant Or Right Outstanding Weighted Average Exercise Price Weighted Average Exercise Price, Ending Balance Weighted Average Exercise Price, Beginning Balance Class of warrant or right outstanding weighted average remaining life. Class Of Warrant Or Right Outstanding Weighted Average Remaining Life Weighted Average Remaining Life Commitment And Contingencies [Line Items] Commitment And Contingencies [Line Items] Commitment And Contingencies [Line Items] Commitment And Contingencies [Table] Commitment And Contingencies [Table] Commitment And Contingencies [Table] Commitments and Contingencies COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Text Block] Contingencies and Commitments Common Stock, Capital Shares Reserved for Future Issuance Number of shares reserved for issuance Common Stock Capital Shares Reserved For Future Issuance [Line Items] Common Stock Capital Shares Reserved For Future Issuance [Line Items] Common Stock Capital Shares Reserved For Future Issuance [Line Items] Common Stock Capital Shares Reserved For Future Issuance [Table] Common Stock Capital Shares Reserved For Future Issuance [Table] Common Stock Capital Shares Reserved For Future Issuance [Table] Common Stock [Member] Common Stock Common Stock, Par or Stated Value Per Share Common stock shares par value Common Stock, Shares Authorized Common stock shares authorized Common stock authorized Common Stock, Shares, Issued Common stock shares issued Common Stock, Shares, Outstanding Common stock shares outstanding Common Stock, Value, Issued Common stock, $0.001 par value, 500,000,000 shares authorized 70,550,763 shares issued and outstanding (2014 - 20,318,815) Common stock warrants - equity treatment. Common Stock Warrants Equity Treatment Common stock warrants - equity treatment Common stock warrants - liability treatment. Common Stock Warrants Liability Treatment Common stock warrants - liability treatment Consolidation, Policy [Policy Text Block] Principles of Consolidation Conversion of accounts payable to common stock. Conversion Of Accounts Payable To Common Stock Conversion of accounts payable to common stock, Share Conversion of accounts payable to common stock amount. Conversion Of Accounts Payable To Common Stock Amount Conversion of accounts payable to common stock, Amount Conversion Of Debt Obligations Into Common Stock [Abstract] Conversion Of Debt Obligations Into Common Stock [Abstract] Conversion of debt obligations into common stock: Convertible notes promissory notes loan payable related party due to related parties and accrued interest converted into series A and B preferred stock and immediately converted into common stock. Convertible Notes Promissory Notes Loan Payable Related Party Due To Related Parties And Accrued Interest Converted Into Series A And B Preferred Stock And Immediately Converted Into Common Stock Convertible notes, promissory notes, loan payable-related party, due to related parties and accrued interest converted into Series A and B preferred stock and immediately converted into commons stock,Share Convertible notes promissory notes loan payable related party due to related parties and accrued interest converted into series a and b preferred stock and immediately converted into common stock amount. Convertible Notes Promissory Notes Loan Payable Related Party Due To Related Parties And Accrued Interest Converted Into Series A And B Preferred Stock And Immediately Converted Into Common Stock Amount Convertible notes, promissory notes, loan payable-related party, due to related parties and accrued interest converted into Series A and B preferred stock and immediately converted into commons stock,Amount Costs and Expenses [Abstract] Operating expenses: Current Fiscal Year End Date Current Fiscal Year End Date Debt Conversion, Converted Instrument, Amount Convertible notes payable Debt Instrument [Axis] Debt Instrument [Axis] Debt Instrument, Interest Rate, Stated Percentage Annual interest rate Debt Instrument [Line Items] Debt Instrument [Line Items] Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Debt Instrument, Periodic Payment Settlement of debt Schedule of Long-term Debt Instruments [Table] Schedule of Long-term Debt Instruments [Table] Deferred Income Taxes and Other Assets [Abstract] Deferred tax assets: Deferred Policy Acquisition Cost, Foreign Currency Translation Adjustment and Other Foreign exchange translation adjustment Deferred Tax Assets, Gross Total deferred tax assets Deferred tax assets license agreement. Deferred Tax Assets License Agreement License agreements Deferred Tax Assets, Net of Valuation Allowance Deferred tax assets, net of valuation allowance Deferred Tax Assets, Operating Loss Carryforwards Net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards, Foreign Federal net operating loss carryforwards Deferred tax assets operating loss carryforwards reversal. Deferred Tax Assets Operating Loss Carryforwards Reversal Reversal of deferred tax assets Deferred Tax Assets, Operating Loss Carryforwards, State and Local State NOLs Deferred Tax Assets, Tax Credit Carryforwards, Research Research and development Research and development tax credit carryforwards Deferred Tax Assets, Valuation Allowance Valuation allowance Deferred tax stock based compensation. Deferred Tax Stock Based Compensation Stock-based compensation Deferred tax technology licensing fee. Deferred Tax Technology Licensing Fee Technology licensing fee Derivative Liability, Fair Value, Gross Liability Derivative liability - warrants Derivative, Fair Value, Net Total Derivative, Fair Value, Net [Abstract] Derivative, Fair Value, Net [Abstract] Derivative, Gain (Loss) on Derivative, Net Changes in fair value of derivative liabilities Derivative Instruments Not Designated as Hedging Instruments, Gain Fair value derivative liability - conversion option at conversion Derivative Liability Derivative liabilities Derivative Liability, Current Derivative liability - warrants Derivatives and Fair Value [Text Block] Derivative Liability Derivatives, Fair Value [Line Items] Derivatives, Fair Value [Line Items] Derivatives, Policy [Policy Text Block] Derivative Liability Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document Fiscal Period Focus Document Fiscal Period Focus Document Fiscal Year Focus Document Fiscal Year Focus Document Period End Date Document Period End Date Document Type Document Type Earnings Per Share [Abstract] Earnings Per Share [Abstract] Earnings Per Share, Basic and Diluted Basic and Diluted Net Loss per Share Earnings Per Share, Policy [Policy Text Block] Loss per Common Share Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Share based compensation recognized period Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options Stock based compensation cost Entity Central Index Key Entity Central Index Key Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Entity Current Reporting Status Entity Current Reporting Status Entity Filer Category Entity Filer Category Entity Public Float Entity Public Float Entity Registrant Name Entity Registrant Name Entity Voluntary Filers Entity Voluntary Filers Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Equity [Abstract] Equity [Abstract] Equity Component [Domain] Equity Component [Domain] Equity units issued price per unit. Equity Units Issued Price Per Unit Sales price per unit Exercise of warrants amount. Exercise Of Warrants Amount Exercise of warrants, Amount Exercise of warrants share. Exercise Of Warrants Share Exercise of warrants, Share Extinguishment of Debt, Gain (Loss), Income Tax Loss on extinguishment of debt Extinguishment of Debt, Gain (Loss), Net of Tax Permanent differences- Non-cash loss on extinguishment of debt Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Table] Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Table] Fair Value Assumptions and Methodology for Assets and Liabilities [Abstract] Fair Value Assumptions and Methodology for Assets and Liabilities [Abstract] Fair Value Assumptions, Expected Dividend Rate Dividend yield (per share) Fair Value Assumptions, Expected Term Contractual term (years) Fair Value Assumptions, Expected Volatility Rate Volatility (annual) Fair Value Assumptions, Risk Free Interest Rate Risk-free rate Fair Value, Hierarchy [Axis] Fair Value, Hierarchy [Axis] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Fair Value Hedging 1 [Member] Fair Value Hedging 1 [Member] Carrying Value [Member] Fair Value Hedging [Member] Fair Value [Member] Fair Value, Inputs, Level 3 [Member] Fair Value, Inputs, Level 3 [Member] Fair Value Measurement, Policy [Policy Text Block] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Fair Value Of Additional Warrants Issued Fair Value Of Additional Warrants Issued Fair value of warrants issued on May 28, 2015 Fair Value, Option, Changes in Fair Value, Gain (Loss) Change in fair value of warrant liability Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table] Fair Values Derivatives, Balance Sheet Location, by Derivative Contract Type [Table] Financial assets and liabilities measured at fair value on recurring basis. Financial Assets And Liabilities Measured At Fair Value On Recurring Basis Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis Finders fee on exercise of warrants. Finders Fee On Exercise Of Warrants Finders' fee on exercise of warrants Foreign Currency Transaction Gain (Loss), before Tax Foreign exchange (loss) gain Gain (Loss) on Derivative Instruments, Net, Pretax Fair value of warrants recognized as derivative liabilities in January and March 2015 Financing Gain (Loss) Related to Litigation Settlement Loss on settlement agreement Gains (Losses) on Extinguishment of Debt Loss on extinguishment of debt General and Administrative Expense General and administrative Income Statement [Abstract] Income Statement [Abstract] Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Income Tax Examination, Penalties and Interest Accrued Accrued amount for payment of interest and penalties Income Tax Expense (Benefit) Income tax expense Income tax provision (benefit) Effective Income Tax Rate Reconciliation, Amount [Abstract] Permanent differences Income Tax [Line Items] Income Tax [Line Items] Income Tax [Line Items] Income Tax, Policy [Policy Text Block] Income Taxes Income tax reconciliation change in fair value of derivative liability. Income Tax Reconciliation Change in Fair Value of Derivative Liability Permanent differences- Change in fair value of derivative liabilities Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount U. S. federal statutory rate Effective Income Tax Rate Reconciliation, Other Reconciling Items, Amount Other Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount State taxes, net of federal benefit Income tax reconciliation tax write off of net operating losses. Income Tax Reconciliation Tax Write Off Of Net Operating Losses Permanent differences- Write off of net operating loss Income Tax [Table] Income Tax [Table] Income Tax [Table] Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts payable and accrued liabilities Increase (Decrease) in Derivative Liabilities Changes in fair value of derivative liabilities Increase (Decrease) in Due to Related Parties Due to related parties Increase (Decrease) in Interest Payable, Net Accrued interest Increase (Decrease) in Notes Payable, Related Parties Promissory notes, related party Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Other Accounts Payable Accounts payable settled in common stock Increase (Decrease) in Prepaid Expense Prepaid expenses and deposits Interest and Debt Expense Non-cash interest and finance charges Interest and financing charges Interest on Convertible Debt, Net of Tax Accretion of discount on convertible notes January And March Two Thousands Fifteen Share Purchase Warrants [Member] January And March Two Thousands Fifteen Share Purchase Warrants [Member] January and March 2015 Share Purchase Warrants [Member] Lease Arrangement, Type [Axis] Lease Arrangement, Type [Axis] Lease Arrangement, Type [Domain] Lease Arrangement, Type [Domain] Lease Expiration Date Lease expiration date Lessor Leasing Arrangements, Operating Leases, Term of Contract Term of lease Liabilities and Equity Total liabilities and stockholder's deficit Liabilities and Equity [Abstract] LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT) Liabilities, Current Total Current Liabilities Liabilities, Current [Abstract] Current Liabilities Financial and Nonfinancial Liabilities, Fair Value Disclosure Balance - December 31, 2015 Balance - December 31, 2014 License And Assignment Commitment [Member] License And Assignment Commitment [Member] License and Assignment Commitment [Member] Amount of required minimum license maintenance fees payments due in the second fiscal year following the latest fiscal year. Licenses Maintenance Fee Future Minimum Payments Due In Two Years Payment of annual license maintenance fees Amount of required minimum license maintenance fees payments due thereafter following the latest fiscal year. Licenses Maintenance Fee Future Minimum Payments Due Thereafter Payment of annual license maintenance fees Loans and Leases Receivable, Gross, Commercial Promissory note, related party Category of Item Purchased [Axis] Category of Item Purchased [Axis] Long-term Purchase Commitment, Category of Item Purchased [Domain] Long-term Purchase Commitment, Category of Item Purchased [Domain] Loss on settlement agreement. Loss On Settlement Agreement Loss on settlement agreement May Two Thousands Fifteen Restructuring [Member] May Two Thousands Fifteen Restructuring [Member] May 2015 Restructuring [Member] Measured at fair value. Measured At Fair Value Schedule of Changes in Level 3 Liabilities Measured at Fair Value Noncontrolling Interest Disclosure [Text Block] Net Loss Per Share Applicable to Common Shareholder Nature of Operations [Text Block] Nature of Operations Net Cash Provided by (Used in) Financing Activities NET CASH PROVIDED BY FINANCING ACTIVITIES Net Cash Provided by (Used in) Financing Activities [Abstract] CASH FLOWS FROM FINANCING ACTIVITIES Net Cash Provided by (Used in) Operating Activities NET CASH USED IN OPERATING ACTIVITIES Net Cash Provided by (Used in) Operating Activities [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES Net Income (Loss) Attributable to Parent Net loss Net Loss for the Period Net loss per share. Net Loss Per Share [Table Text Block] Net Loss per Share New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued Accounting Pronouncements Noncash or part noncash transaction fair value of warrants issued. Noncash Or Part Noncash Transaction Fair Value Of Warrants Issued Fair value of issuance of warrants in January and March 2015 financing Noncash or part noncash transaction issuance of additional warrants. Noncash Or Part Noncash Transaction Issuance Of Additional Warrants Issuance of additional warrants in May 28, 2015 transaction Noncash or part noncash transaction reclassification of warrant liabilities to equity Noncash Or Part Noncash Transaction Reclassification Of Warrant Liabilities To Equity Reclassification of Derivative Warrant Liabilities to Equity at exercise date Noncontrolling Interest [Abstract] Noncontrolling Interest [Abstract] Nonoperating Income (Expense) [Abstract] Other Income (Expense) Notes Payable Promissory notes Notes Payable [Abstract] Notes Payable [Abstract] Notes Payable, Current Outstanding promissory notes Number of common stock included in unit offering. Number Of Common Stock Included In Unit Offering Number of common stock included in equity unit Number of equity units issued. Number Of Equity Units Issued Units issued Number of ovarian cancer patients. Number Of Ovarian Cancer Patients Number of ovarian cancer patients Number of preferred stock shares converted to common stock. Number Of Preferred Stock Shares Converted To Common Stock Conversion of shares into common stock Number of votes per share. Number Of Votes Per Share Voting right Number of warrants exercised. Number Of Warrants Exercised Number of warrants exercised Number of Warrants, Exercised Number of warrants extinguished or expired. Number Of Warrants Extinguished Or Expired Number of Warrants, Extinguished or expired Number of warrants issued. Number Of Warrants Issued Number of Warrants, Issued Office Property Lease Agreement [Member] Office Property Lease Agreement [Member] Office Property Lease Agreement [Member] Officer And Director [Member] Officer And Director [Member] Officer and Director [Member] Omnibus Stock Plan Two Thousand Fourteen [Member] Omnibus Stock Plan Two Thousand Fourteen [Member] 2014 Omnibus Stock Option Plan [Member] Operating Income (Loss) Loss from Operations Operating Leases, Rent Expense, Minimum Rentals Minimum rental payments Option Indexed to Issuer's Equity, Shares Common stock options Option Indexed to Issuer's Equity, Strike Price Strike price Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Other Comprehensive (Income) Loss, Pension and Other Postretirement Benefit Plans, Tax [Abstract] Other comprehensive income Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Gain (Loss) Arising During Period, Net of Tax Foreign exchange translation adjustment Other Comprehensive Income (Loss), before Tax TOTAL COMPREHENSIVE LOSS Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax Foreign exchange loss Other Liabilities, Current Research agreement obligations Payment for upfront licensing fee. Payment For Upfront Licensing Fee Upfront license fee payments Percentage of breast cancers. Percentage Of Breast Cancers Percentage of breast cancers Percentage of finders fee. Percentage Of Finders Fee Finders fee, Percentage Percentage of ovarian cancers. Percentage Of Ovarian Cancers Percentage of ovarian cancers Percentage of royalty on sale of product. Percentage Of Royalty On Sale Of Product Percentage of royalty on sales of the licensed product Permanent differences other permanent differences. Permanent Differences Other Permanent Differences Permanent differences- Other permanent differences Preferred Stock, Par or Stated Value Per Share Preferred stock par value Preferred Stock, Shares Authorized Preferred stock par value Preferred stock shares authorized/designated Preferred Stock, Shares Issued Preferred stock issued Preferred Stock, Shares Outstanding Preferred stock outstanding Preferred Stock, Value, Issued Convertible preferred stock, $0.001 par value - 5,000,000 shares authorized Prepaid Expense, Noncurrent Prepaid expenses and deposits Reclassification, Policy [Policy Text Block] Prior Period Reclassifications Private placement amount. Private Placement Amount Private placement (net of finders' fee) Amount Private Placement [Member] Private Placement [Member] Private placement share. Private Placement Share Private placement (net of finders' fee) share Proceeds from Convertible Debt Convertible notes issuance Proceeds from Issuance of Common Stock Issuance of shares, net of finders' fee Proceeds from Related Party Debt Loans payable, related party Proceeds from Warrant Exercises Proceeds from exercise of warrants Proceeds from warrants exercised Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Promissory Note Related Party [Text Block] Promissory Note Related Party [Text Block] Promissory Note, Related Party Promissory Notes Due In Two Thousand Twelve [Member] Promissory Notes Due In Two Thousand Twelve [Member] Promissory Notes Due in 2012 [Member] Promissory notes interest. Promissory Notes Interest Amount of promissory notes interest charges Promissory Note [Text Block] Promissory Note [Text Block] Promissory Notes Related Party Transaction [Line Items] Related Party Transaction [Line Items] Related Party Transactions [Abstract] Related Party Transactions [Abstract] Repayment of Notes Receivable from Related Parties Repayment of promissory notes Research and Development [Abstract] Research and Development [Abstract] Research and Development Expense Research and development Research and Development Expense, Policy [Policy Text Block] Research and Development Costs Research, Development, and Computer Software Disclosure [Text Block] Research Agreements Research Tax Credit Carryforward [Member] Research and Development Tax Credit Carryforwards [Member] Restructuring Agreement Number Of Warrants Issued Ratio Restructuring Agreement Number Of Warrants Issued Ratio Replacement of warrants Restructuring Plan [Axis] Restructuring Plan [Axis] Restructuring Plan [Domain] Restructuring Plan [Domain] Retained Earnings (Accumulated Deficit) Accumulated deficit Retained Earnings [Member] Retained Earnings / Accumulated Deficit Sale of Stock [Domain] Sale of Stock [Domain] Scenario, Forecast [Member] Scenario, Forecast [Member] Scenario, Unspecified [Domain] Scenario, Unspecified [Domain] Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Summary of Effects of Temporary Differences that Give Rise to Significant Portions of the Deferred Tax Assets Schedule of Related Party Transactions, by Related Party [Table] Schedule of Related Party Transactions, by Related Party [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] Share Purchase Options Schedule or Description of Weighted Average Discount Rate [Table Text Block] Weighted Average Assumptions Series A B And C Warrants [Member] Series A B And C Warrants [Member] Series A B and C Warrants [Member] Series A Preferred Stock [Member] Series A Preferred Stock [Member] Series A Warrant [Member] Series A Warrant [Member] Seriesa Warrant [Member] Series B Preferred Stock [Member] Series B Preferred Stock [Member] Series B Warrant [Member] Series B Warrant [Member] Series B Warrant [Member] Series C Warrant [Member] Series C Warrant [Member] Series C Warrant [Member] Series D Warrant [Member] Series D Warrant [Member] Series D Warrant [Member] Series E Warrant [Member] Series E Warrant [Member] Series E Warrant [Member] Share-based Compensation Stock based compensation Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Shares granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value Fair value of common stock Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend rate Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected life of options in years Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Weighted-average volatility Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk-free rate Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value Intrinsic Value, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Number of Options Exercisable, Ending Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Weighted Average Exercise Price Exercisable, Ending Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Weighted Average Remaining Life, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period Number of Options Outstanding, Cancelled/Forfeited Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Cancelled/Forfeited Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Grant Date Intrinsic Value Intrinsic Value, Issued Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Number of Options Outstanding, Issued Share Based Compensation Arrangement by Share Based Payment Award Options Issued Weighted Average Remaining Contractual Term Share Based Compensation Arrangement by Share Based Payment Award Options Issued Weighted Average Remaining Contractual Term Weighted Average Remaining Life, Options Issued Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Intrinsic Value Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Number of Options Outstanding, Ending Balance Number of Options Outstanding, Beginning Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted Average Exercise Price Outstanding, Ending Balance Weighted Average Exercise Price Outstanding, Beginning Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Weighted Average Remaining Life, Outstanding Equity Award [Domain] Equity Award [Domain] Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Issued Share-based Compensation, Option and Incentive Plans, Director Policy [Policy Text Block] Stock-Based Compensation Share Purchase Warrants [Member] Share Purchase Warrants [Member] Stock Purchase Warrants [Member] Tabular disclosure of the share purchase warrants. Share Purchase Warrants Table [Text Block] Share Purchase Warrants Shares, Issued Ending Balance, Share Beginning Balance, Share Shares issued in settlement agreement amount. Shares Issued In Settlement Agreement Amount Shares issued in settlement, Amount Shares issued in settlement agreement shares. Shares Issued In Settlement Agreement Shares Shares issued in settlement, Share Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Class of Stock [Axis] Class of Stock [Axis] Equity Components [Axis] Equity Components [Axis] Statement [Line Items] Statement [Line Items] Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Scenario [Axis] Scenario [Axis] Statement [Table] Statement [Table] Stock based compensation amount. Stock Based Compensation Amount Stock- based compensation, Amount Stock based compensation shares. Stock Based Compensation Shares Stock- based compensation, Share Stock Granted, Value, Share-based Compensation, Forfeited Non-qualified stock options cancelled, Value Stockholders' Equity Attributable to Parent Ending Balance, Amount Beginning Balance, Amount Total Stockholders' Deficit Stockholders' Equity Attributable to Parent [Abstract] Stockholders' Equity (Deficit) Stockholders' Equity Note, Stock Split, Conversion Ratio Reverse stock split Stockholders' Equity, Reverse Stock Split Reverse stock split Equity Option [Member] Stock Options [Member] Subsequent Event [Member] Subsequent Event [Member] Subsequent Event Type [Axis] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Subsequent Warrant Issuance [Member] Subsequent Warrant Issuance [Member] Subsequent Warrant Issuance [Member] Sale of Stock [Axis] Sale of Stock [Axis] Summary Of Expected Tax Expense Benefit Based On Federal Statutory Rate Is Reconciled With Actual Tax Provision Benefit Table [Text Block] Summary Of Expected Tax Expense Benefit Based On Federal Statutory Rate Is Reconciled With Actual Tax Provision Benefit Table [Text Block] Summary of Expected Tax Expense (Benefit) Based on the U.S. Federal Statutory Rate is Reconciled with the Actual Tax Provision (Benefit) Supplemental Cash Flow Information [Abstract] SUPPLEMENTAL SCHEDULE OF NON-CASH ACTIVITIES Tax Credit Carryforward [Axis] Tax Credit Carryforward [Axis] Tax credit carryforward expiration year range end. Tax Credit Carryforward Expiration Year Range End Tax credit carryforwards expiration year end Tax credit carryforward expiration year range start. Tax Credit Carryforward Expiration Year Range Start Tax credit carryforwards expiration period Tax Credit Carryforward, Name [Domain] Tax Credit Carryforward, Name [Domain] Text Block [Abstract] Text Block [Abstract] Title of Individual [Axis] Title of Individual [Axis] Relationship to Entity [Domain] Relationship to Entity [Domain] Trading Symbol Trading Symbol Unrecognized Tax Benefits Unrecognized tax benefits Unregistered Common Stock [Member] Unregistered Common Stock [Member] Unregistered Common Stock [Member] Use of Estimates, Policy [Policy Text Block] Use of Estimates Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Change in valuation allowance Valuation allowance decreased amount Valuation methodology. Valuation Methodology Valuation Methodology Warrants issued finders fee and offering costs. Warrants Issued Finders Fee And Offering Costs Finders fee and issuance costs Weighted Average Number of Shares Outstanding, Basic and Diluted Weighted Average Number of Common Shares Outstanding